Myeloid Sarcoma: A Mediastinal Masquerader

Primary Mediastinal Synovial Sarcoma

Synovial sarcoma occurs predominantly in the soft tissues of the extremities, but is exceedingly rare in the mediastinum. It has overlapping histological and immunophenotypic features with other tumours in the differential diagnosis. We report a case of a patient who had an incidental finding of such a tumour. Because of the rarity of this tumour in the mediastinum, optimal therapy is unknown a...

Primary Mediastinal Synovial Sarcoma

We report a rare case of a primary mediastinal synovial sarcoma. A 44-year-old man had a well-defined tumor in the left posterior mediastinum involving the left lower lobe of the lung, as detected on chest computed tomography, and underwent an en bloc excision and a left lower lobectomy. Grossly, the tumor measured 8.0 cm in the greatest diameter, with a solid and tan-white cut surface. Histolo...

Isolated Mediastinal Myeloid Sarcoma: A Rare Presentation of Extramedullary Leukemic Tumor

Myeloid sarcoma is a rare solid tumor consisting of myeloid blasts that proliferate in any extramedullary site. It can present before, concurrent with or after the diagnosis of acute myeloid leukemia [AML] or other myeloproliferative disorders. The most common sites include skin, gum, lymph nodes, soft tissue, periosteum, and bone. Here, we present a 66-year-old male with a history of bladder c...

Cutaneous Metastatic Undifferentiated Pleomorphic Sarcoma from a Mediastinal Sarcoma

Undifferentiated pleomorphic sarcoma, known as malignant fibrous histiocytoma, is a malignant neoplasm that arises in both soft tissue and bones. In 2002, the World Health Organization declassified malignant fibrous histocytoma as a formal diagnostic entity and renamed it 'undifferentiated pleomorphic sarcoma not otherwise specified.' It most commonly occurs in the lower extremities and rarely ...

Myeloid Sarcoma